sabotage

[1]	undermine , countermine , counteract , subvert , weaken
[2]	undermine , subvert , disrupt , spoil , ruin , cripple , damage , incapacitate , disable , destroy , wreck , (Colloq) (Brit) throw a spanner in(to) the works , (US) throw a monkey wrench into the machinery , (Slang) (Brit) queer (someone's pitch)

[1]	destruction , damage , wrecking , impairment
[2]	subversion , treachery , treason