spite

[1]	hurt , annoy , irritate , wound , injure , vex , upset , bruise , offend , disconcert , offend , provoke , discomfit , pique , put out , hurt , injure , wound , (Colloq) peeve , get under (someone's) skin , needle , (US) do a number on

[1]	spitefulness , malice , maliciousness , maliciousness , malice , spitefulness , venom , malevolence , malignity , ill will , venom , spleen , rancour , animosity , gall (and wormwood) , resentment , bitterness , hostility , antagonism , hatred , hate , (Colloq) bitchiness
[2]	in spite of , cattiness , bitchiness , despite , notwithstanding , spitefulness , nastiness , regardless of , ignoring , in defiance of