trouble

[1]	bother , upset , anguish , alarm , worry , afflict , agitate , disquiet , discomfit , make uncomfortable , grieve , perturb , discommode , inconvenience , discompose , discountenance , put out , burden , encumber , weigh down
[2]	annoy , irritate , irk , vex , bother , plague , pester , torment , harass , hector , harry , provoke , nettle , exasperate , ruffle , (Colloq) get/grate on (someone's) nerves , give (someone) a hard time , get under (someone's) skin
[3]	discommode , incommode , impose on , inconvenience , put out , thank
[4]	care , be concerned , take the trouble/the time , go to the trouble , bother , exert (oneself) , concern (oneself) , take pains
[5]	disturb , upset
[6]	put out , inconvenience , disoblige , discommode , incommode , bother
[7]	perturb , unhinge , disquiet , cark , distract , disorder
[8]	trouble oneself , bother , inconvenience oneself
[9]	ail , pain

[1]	problem
[2]	fuss , bother , hassle
[3]	difficulty
[4]	worry , distress , worry , concern , difficulty , discomfort , unpleasantness , inconvenience , vexation , grief , woe , affliction , disquiet , suffering , tribulation , anxiety , torment , anguish , strife
[5]	annoyance , bother , tormenter , irritation , nuisance , nag , heckler , pest , (Slang) (US) nudnik
[6]	disorder , agitation , row , disturbance , turbulence , tumult , upset , dissatisfaction , unrest , discord , dispute , turmoil , rebellion , revolt , uprising , outbreak , fighting , fight , skirmishing , skirmish
[7]	affliction , defect , disability , disease , ailment , illness , sickness , disorder , complaint
[8]	in trouble , in deep trouble , in a mess , in a predicament , in dire straits , (Colloq) in a pickle , in hot water , on the spot , in a scrape , (Slang) (Brit) in shtook/shtuk/shtuck/schtuck , (Colloq) (Slang) in deep shit , up shit creek (without (the vestige of) a paddle)unmarried/unwed and impregnated/pregnant/with child/expecting/in a delicate condition/(Colloq) in a family way